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K-Ras ligand-Linker Conjugate 3 camine 27)28)29-24(32)20-4-2-19(3-5-20)17-30-12-14-33-15-13-30/h2-7

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27)28)29-24(32)20-4-2-19(3-5-20)17-30-12-14-33-15-13-30/h2-7

K-Ras ligand-Linker Conjugate 3 camine 27)28)29-24(32)20-4-2-19(3-5-20)17-30-12-14-33-15-13-30/h2-7K Ras ligand Linker Conjugate 3 (Compound 001371) incorporates a ligand for K Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 3 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information CAS Number: 2378261 87 9 Molecular Weight: 944. 15

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